ECD (gene)

Ecdysoneless homolog (Drosophila)

Identifiers

ECD; GCR2; HSGT1

External IDs

MGI: 1917851 HomoloGene: 5256 GeneCards: ECD Gene

Gene Ontology
Molecular function	• transcription coactivator activity
Cellular component	• nucleus • cytoplasm
Biological process	• regulation of glycolysis • regulation of transcription, DNA-dependent • transcription from RNA polymerase II promoter
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 10:
74.89 – 74.93 Mb

Chr 14:
21.14 – 21.17 Mb

PubMed search

[1]

[2]

Protein SGT1 is a protein that in humans is encoded by the ECD gene.^[1]^[2]^[3]

References

^ Sato T, Jigami Y, Suzuki T, Uemura H (Feb 1999). "A human gene, hSGT1, can substitute for GCR2, which encodes a general regulatory factor of glycolytic gene expression in Saccharomyces cerevisiae". Mol Gen Genet 260 (6): 535–40. doi:10.1007/s004380050926. PMID 9928932.
^ Gaziova I, Bonnette PC, Henrich VC, Jindra M (May 2004). "Cell-autonomous roles of the ecdysoneless gene in Drosophila development and oogenesis". Development 131 (11): 2715–25. doi:10.1242/dev.01143. PMID 15128659.
^ "Entrez Gene: ECD ecdysoneless homolog (Drosophila)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11319.

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Bork JM, Peters LM, Riazuddin S et al. (2001). "Usher Syndrome 1D and Nonsyndromic Autosomal Recessive Deafness DFNB12 Are Caused by Allelic Mutations of the Novel Cadherin-Like Gene CDH23". Am. J. Hum. Genet. 68 (1): 26–37. doi:10.1086/316954. PMC 1234923. PMID 11090341. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1234923.
Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
Nowotny M, Spiechowicz M, Jastrzebska B et al. (2003). "Calcium-regulated interaction of Sgt1 with S100A6 (calcyclin) and other S100 proteins". J. Biol. Chem. 278 (29): 26923–8. doi:10.1074/jbc.M211518200. PMID 12746458.
Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
Rual JF, Venkatesan K, Hao T et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Olsen JV, Blagoev B, Gnad F et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.

ECD (gene)

References

Further reading